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Cardiovascular Pathophysiology
In the Setting of Spinal Cord Injury

Dr. West’s group uses small and large in vivo animal models to understand how the circuitry that controls the cardiovascular system changes following injury and what the downstream impact of these changes are for heart and blood vessel function. They also use these models to test the efficacy of novel therapies in the both the acute and chronic setting following injury. In the clinical and athletic spinal cord injury population, his group has conducted a number of mechanistic and applied studies to, 1) improve the understanding of how best to hemodynamically manage acutely injured patients, and 2) enhance the capacity of the cardiovascular system to enable an improved exercise response.
Blood Flow from the heart

This webinar will introduce the major cardiovascular changes that have been characterized following spinal cord injury in animal models and the clinical population. Chris will share some exciting results from recent studies in which his group has tested the efficacy of novel therapies to improve cardiovascular function. Finally, he will provide his outlook for the future of the field.

Key topics:
  • Identify and define the major cardiovascular changes that occur following spinal cord injury
  • Compare and contrast peripheral and central contributions to cardiovascular dysfunction following spinal cord injury
  • Describe some promising interventions that can be used in the acute and/or chronic setting following spinal cord injury to offset cardiovascular dysfunction