Twelve days after a HeartAssist5® (HA5) left ventricular assist device (LVAD) was implanted into a patient, clinicians at a remote monitoring center noticed a change in the normal pulsatile flow waveform transmitted from the LVAD to the monitoring site. Heart arrhythmia was diagnosed and the patient was notified to see her cardiologist immediately. Medication was prescribed that corrected the problem. Thus, continuous True Flow measured in the LVAD, transmitted to a remote diagnostic site and monitored by clinicians averted a potential crisis for this heart failure patient.
Transonic VAD History Precedes Transonic Itself
Flowmetry in the VAD has a Transonic® history that is older than Transonic itself. Our principal Mr. Drost came from the Netherlands to the USA in the early 1970s on the invitation of Dr. Yukihiko Nose, to design an ultrasonic flowsensor for an artificial heart that Dr. Nose was developing at the Cleveland Clinic. Due to grant funding issues (sounds familiar?), Mr. Drost landed a job designing chronic ultrasonic Flowsensors at Cornell University instead (1973-1983) – and this morphed into Transonic Systems (1983-present) – and realization of Dr. Nose’s original assignment to Mr. Drost, “Design me a flowsensor for the artificial heart.”
LVADs as “Bridge to Transplant” or “Destination Therapy”
Today, more than 20,000 heart failure patients throughout the world have been implanted with LVADs temporarily as a “bridge to transplant” or, in some instances, permanently as a “destination therapy.” Throughout the history of ventricular assist device development, Transonic flow technology has been used to test prototype VADs/LVADs. In the case of the HA5, Transonic True Flow has been incorporated in its clinical axial pump and has paid dividends for the woman whose arrhythmia was detected by monitoring of True Flow by the customized Transonic Flowsensor, positioned on the HA5 outflow cannula. This real-time flow data is transmitted to an implanting center where it can alert clinicians to potential problems before any clinical symptoms appear. The HA5 pump is a derivative of the former DeBakey MicroMed VAD, a 2002 NASA Invention of the Year, which was developed using supercomputer simulation originally designed to model fluid flow through NASA rocket engines.
Also view this case study by Spiliopoulos: "Beneficial Aspects of Real Time Flow Measurements for the Management of Acute Right Ventricular Heart Failure Following Continuous Flow Ventricular Assist Device (VAD) Implantation"
For more information about Transonic‘s OEM collaborations, “Transonic Inside,” click here.
To learn more about ReliantHeart’s HeartAssist5®, click here.
Or watch some informational videos here: