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Ordering T106/T206 Flowprobes

R & S-Series for Acute/Chronic Animal Studies

 

 

Flowprobes Configured to Application
Species? Vessel? Duration?

When ordering flowprobes for acute or chronic animal studies, Transonic Customer Service will gladly assist in configurating the most appropriate flowprobe for your application. Important information includes:

  • FLOWMETER MODEL #
  • ANIMAL MODEL
  • VESSEL (estimated diameter)
  • TYPE OF STUDY (see below)
    • ACUTE STUDY (<24 hours with animal under anesthesia/open chest or belly)
    • CHRONIC STUDY (probe implanted with measurements on conscious animal)
      • Duration: (How long, hrs, days, weeks, months)

probe_diagram
Schematic shows information necessary to order perivascular R & S-Series flowprobes (listed to the left).

 

 

R- & S-Series Flowprobes: indicate
  • PROBE SIZE (determined by vessel's outer diamter in mm)
  • PROBE SERIES (R Series or S-Series)
  • CABLE ORIENTATION,
    • side/parrallel to vessel,
    • back/perpendicular to vessel
    • L, lateral
  • REFLECTOR STYLE (see below)
    • "L" with slide
    • "J" with or without slide cover
    • "U" bracket with or silicone flange , shield or wrap
  • CABLE LENGTH typical length is 1 meter
  • CONNECTOR STYLE specific tro flowmeter models (see below)
  • EXTENSION CABLE
  • CALIBRATION: Acute or Chronic (see below)
  • Custom Features

Nanoprobes

Probe Configuration Key

Example: 1.5RB
1.5
= probe size in mm
R = indicates probe Series (R)
B
= indicates back cable exit

Example: 2.5SL
2.5
= probe size in mm
S = indicates probe Series (S)
L
= indicates lateral cable exit

Example: 8RS
8
= probe size in mm
R = indicates probe Series (R)
S
= indicates side cable exit

 

 

S-Series Probes

Catalog
#

Size
mm

VESSEL
OD mm
chronic

VESSEL
OD mm
acute

CABLE EXIT,
back(B), side (S),
lateral (L)

Cable Lgth
meters

2S

2 mm

1.3 - 1.8

1.5 - 2.0

2SS, 2SB

1 meter

2.5S

2.5 mm

1.5 - 2.4

1.8 - 2.5

2.5SS, 2.5SB, 2.5SL

1 meter

3S

3 mm

2.4 - 3.4

2.5 - 3.7

3SS, 3SB

1 meter

4S

4 mm

3.0 - 4.0

3.3 - 4.4

4SS, 4SB

1 meter

6S

6 mm

4.0 - 6.0

4.4 - 6.6

6SB, 6SS

1 meter

8S

8 mm

5.8 - 8.0

6 - 8.8

8SB, 8SS

1 meter

10S

10 mm

7.3 - 10

8.3 - 11

10SB, 10SS

1 meter

12S

12 mm

8.6 - 12

9.8 - 13

12SB, 12SS

1 meter

14S

14 mm

10 - 14

11.3 - 15

14SB,14SS

1 meter

16S

16 mm

12 - 16

13.3 - 17.7

16SB, 16SS

1 meter

20S

20 mm

14 - 19

16 - 21

20SB, 20SS

1 meter

 

 

Reflectors for R & S-Series Probes

Catalog
#

Size
mm

VESSEL
OD mm
chronic

VESSEL
OD mm
acute

CABLE EXIT,
back(B), side (S),
lateral (L)

Cable Lgth
meters

1R

0.5 mm

0.5 - 1.0

0.7 - 1.20

 

 

1.5R

1.5 mm

1.0 - 1.5

1.2 - 1.8

 

 

2R

2 mm

1.3 - 2.3

1.8 - 2.5

2RS, 2RB

1 meter

3R

3 mm

1.9 - 3.3

2.5 - 3.7

3RS, 3RB

1 meter

4R

4 mm

1.9 - 3.3

3.3-4.4

4RS,4RB

1 meter

5R

5 mm

2.7 - 5.0

3.8 - 5.3

5RS, 5RB

1 meter

6R

6 mm

3.3 - 6

4.4 - 6.6

6RS, 6RB

1 meter

8R

8 mm

4.4 - 8

6.6 - 8.8

8RS, 8RB

1 meter

 

 

Available in three stainless steel configurations: L, J, U

The fixed reflector on flowprobes is critical to accurate measurements because each transducer within the probe body first emits and then receives an ultrasound beam which is reflected from the stationary reflector. The fixed distance of the reflective pathway is crucial for the measurement of ultrasonic transit time.

L- Reflectors
The L-shape reflector has an adjustable slide cover to fully enclose the vessel. Suture holes are provided to stabilize the probe for prolonged applications.

4SB
L Reflector with slide cover

J- Reflectors
The J-shape reflector is available with and without a slide cover. It is useful for undersized or inaccessible vessels.

3SS
J Reflector

U- Reflectors
The U-shaped reflector is equipped with screw mouns on each side of the probe body. To install around the vessel, the reflector is removed from the probe body, is placed around the vessel and is again secured with screws to the probe body.

physpecsideview
U Reflector

 

 

Connectors for T106/T206 Flowmeters

CH10_acute_connector

CS10

CB10_skin_button

CH10: 10-pin connector with embedded ROM
Designed for ease of use in acute flowprobe applications, this snap-in connector houses the complete digital information for the flowprobe. The CH-10 can be plugged directly into the flowmeter or into a CH10 extension cable.

CS10: 10-pin sealed connector with embedded ROM
Implantable connector with conical threaded protective cap has suture hole for easy guiding during subcutaneous tunneling. Complete digital probe information is sealed within connector. The CS10 can be plugged directlu into the flowmeter or into a CH10 extension cable.

 

CB10: 10-pin Skin Button with embedded ROM
For chronic information, the skin button has a removable anchor flange and flat protective cap. Shank comes in three heights (10, 15, 005 20 mm); the cable enters the connector at a right angle. Complete digital probe information is sealed within the connector. The CB10 plugs into a CH10 extension cable. (Typically used in pigs and larger animal models.)

CM4: mini 4-pin sealed connector with separate ROM key
Implantable 4-pin mini-connector has two-threaded protective caps and a digital coded key specific to each probe. Conical cap with suture hole is used for subcutaneous tunneling; a flat cap is provided for pin protection between measurements. Each probe must be used with its serial numbered key and a CM4 extension cable and a flowmeter; CM4S oe CM4B (side or back exit). We recommend our saddleback cuffs as shown in the picture to the right, to stabilize the position for external use.

CM4_in_saddlecuff
CM4 in Saddle Back Cuff

CA4: micro 4-pin sealed connector with separate ROM key
Designed for minimal impact, the 4-pins terminate the cable end with a bare minimum of housing. A cap is provided for limited pin protection. These connectors can be used where delivcate chronic implantation requires the least impact from externalizing the connector end. Each probe must be used with its serial numbered key and a CM4 extension cable to the flowmeter. Only available for 1R, 1.5R, 2S, 2R, 2.5S, 3R, 3S and 4S probes. These connectors are warranted for one implant only.

CA4
CA4 Connector

 

CTSB4: 4-pin skin button with separate ROM key
In this configuration, the implantable 4-pin mini-connector is embedded in a Delrin skin button for chronic implantation. Each probe must be used with its serial numbered key and a CM4 extension cable to the flowmeter. The skin button has a 17 mm diameter long shank, a 19 mm anchor.

 

 

 

Accessories - Coupants for Acute Applications

Surgilube, H-R Jelly, NALCO 1181
Acoutic couplants are used to supplant the air between the vessel and the probe to complete the acoutic pathway during acute studies. Recommedned couplants have acoutic properties similar to blood at a variety of temperatures: saline is a poor acoutic match. One tube of Surgilube or H-R Jelly is supplied with each flowmeter order; large quantities can be ordered directly from local suppliers. NALCO 1181 (suggested only for acute terminal protocols) is a super-absorbent powder which, when mixed with Surgilube, forms a viscous gel which can be an effective couplant at sites where regular couplants melt or are vibrated away.

 

 

Accessories - Coupants for Chronic Applications

Ultracell Sponge
A soft pliable sponge used to cushion highly pulsatile vessels during chronic studies.

Mersilene Mesh
A polyester fiber mesh which can be cemented to or wrapped around the probe and sutured to adjacent tissue to assist in stabilizing the probe at an implant site.

2RSflangeSilicone Coronary Flange
A mesh-reinforced silicone flange cemented around the probe body. Used in chronic LAD coronary artery application to suture probe to myocardium, and in umbilical artery fetal sheep application.

 

 

Saddleback Cuffs for CM4 & CA4 Mini Connectors

CM4_in_saddlecuff

CM4 in Saddle- Back Cuff

Flange style silicone cuffs with suture holes slip over CM4 and CA4 connectors and are sutured to the skin to stabilize the connector in a position where it cannot be reached by the subject. For long-term implnants, rigid flange style cuffs are more durable and longer lasting. Dual cuffs for two probes are available in silicone. Not suitable for subdermal use.

wrapping_stripSilicone Wrapping Strip
Reinforced mesh envelops the probe and is used to retard fat ingress and stabilize the probe at the implant site.

Silicone Shields
U reflectors may be ordered encapsulated in silicone to maintain probe orientation, cushion pulsatile vessels (ascending aorta application) and retard fat ingress (chronic applications). Narrow and wide silicone shileds are available.

A Word about Calibration
Transonic flowprobes are precalibrated at the factory using a gravity-fed constant flow bench setup with water at room temperature
(TN#5) .
This compensates for different acoustic conditions with the use of an acoustic gel for acute applications and fibrous tissue ingrowth in chronic implants.

Transonic Systems calibrates flowprobes differently depending on their intended use. Probes for acute application are calibrated to read 10% higher than probes for chronic implant. Sub-acute applications of only 1-2 days more closely mimic an acute preparation and should be calibrated as such. For probe that are used for both acute and chronic applications, we recommended acute calibration since acute measurements are more often interpreted in absolute terms. In contrast, chronic protocols are generally evaluated in relative terms as changes in flow over time.

Acute versus Chronic

Acute applications defined as terminal experiments under anesthesia, 1 - 8 hours

Chronic experiments mean the probe is implanted; the connector may be externalized and the animal recovers so measurements may be taken on a conscious animal