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Mouse/Rat Pressure Volume Loops
Cardiac pressure volume (PV) loops are considered to be the gold standard in cardiac function assessment and are used to determine myocardial contractility, compliance, muscle energetic and other important quantitative measures of function. PV catheter technology has emerged as the most reliable method to generate real-time ventricular PV loops in the intact heart, particularly now as a result of recent advancements in the field through the use of "admittance" instead of the older "conductance" technology. Scisense PV catheters incorporate the latest admittance technology and high fidelity pressure sensors to meet the stringent demands of rodent cardiovascular research.
Fig 1. Original recording of PV loops from a mouse during IVC occlusion using a 1.2F Scisense ADVantage PV catheter. The catheter was inserted into the LV via the carotid artery in a closed chest mouse. |
Fig 2. Original recording of PV loops from a rat during baseline using a 1.9F Scisense ADVantage PV catheter. The catheter was inserted into the LV via the carotid artery in a closed chest rat. |
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